Conducting composite films based on chitosan or sodium hyaluronate. Properties and cytocompatibility with human induced pluripotent stem cells

• Novel approach for preparation of PANI/polysaccharide composites was proposed. Conducting PANI with chitosan or sodium hyaluronate were prepared. Composites cytocompatible human induced pluripotent stem cells. exhibited antibacterial activity. composite films combining biocompatible polysaccharides conducting polyaniline (PANI) prepared via the in-situ polymerization aniline hydrochloride in presence (SH) (CH). The possess very good cytocompatibility terms adhesion and proliferation two lines cells (hiPSC). Moreover, cardiomyogenesis even formation beating clusters successfully on films. proportion formed cardiomyocytes demonstrated excellent properties tissue engineering stimuli-responsive tissues. testing also activity against E. coli PANI-SH able to reduce bacterial growth from 2 × 10 5 < 1 cfu cm ?2 . Physicochemical characterization revealed that did not notably influence conductivities being ?1 ?2 S ?1 PANI-CH respectively; however, comparison neat PANI, it modified their topography making smoother mean surface roughness 4 (PANI-SH) 14 nm (PANI-CH). combination conductivity, mainly hiPSC opens wide application potential these polysaccharide-based composites.